Diagnosis of DH usually requires at least one skin biopsy , and sometimes a blood test (looking for anti-gliadin, anti-reticulin and anti-endomysial antibodies). Once confirmed, treatment will be lifelong, although severity may wax and wane. Complete elimination of gluten is curative, but improvement takes months. The gluten-free diet is very difficult, as tiny amounts of gluten are in almost all restaurant and prepared foods, gum wrappers and the like. Cutting down on wheat and gluten may reduce the amount of medication needed, but will not be curative.
Dermatitis herpetiformis (DH) is a chronic inflammatory cutaneous disease that presents with a pruritic papulovesicular eruption